• Promotes cardiovascular health, including support for dyslipidemia and elevated LDL-C • Provides the stable and bioavailable form of vitamin B5, necessary for the biosynthesis of coenzyme A • Coenzyme A is needed for multiple cellular effects, including energy production and fatty acid synthesis • Combined in an antioxidant formula, complexed with organic vegetables, berries, and anti-inflammatory botanicals 450 mg per serving allows for dosing used in clinical trials
Indications
• Promotes cardiovascular health, including support for dyslipidemia and elevated LDL-C • Provides the stable and bioavailable form of vitamin B5, necessary for the biosynthesis of coenzyme A • Coenzyme A is needed for multiple cellular effects, including energy production and fatty acid synthesis • Combined in an antioxidant formula, complexed with organic vegetables, berries, and anti-inflammatory botanicals 450 mg per serving allows for dosing used in clinical trials
Ingredients
Each Softgel Contains: D-Pantethine : 450 mg
Softgel (gelatin, glycerin, purified water).
Description
Pantethine is a stable and bioavailable form of vitamin B5 (pantothenic acid), well-recognized for its favourable effects on markers of cardiovascular disease. 1 After initial conversion to pantetheine (two molecules of pantethine linked by a disulfide bridge) by intestinal bacteria, it is ultimately used for the biosynthesis of coenzyme A (CoA). CoA is a carrier of acetyl groups critical to multiple metabolic processes within the cell, including the Krebs (citric acid) cycle, as well as fatty acid and phospholipid metabolism. 1 Pantethine is commonly referred to as the “anti-stress vitamin” because of its broad utility for a wide range of processes, including energy production, cellular signalling, and the regulation of inflammation and immune function. 2
Case-control analysis indicates that higher pantothenic acid levels are associated with a lower risk of coronary heart disease, likely mediated via several mechanisms. 3 Greater intake has been associated with lower C-reactive protein levels, a marker for inflammation. 4,5 Controlled trials with participants at moderate risk of cardiovascular disease, with no inhibition of CoQ10 synthesis, showed that pantethine specifically improves dyslipidemia, including reducing non-HDL-C, triglycerides, and resulting in as much as an 11% decrease in LDL-C (vs. 3% increase with the placebo).6–8 Additionally, pantethine provides protection against LDL-C peroxidation, an independent risk factor for atherosclerotic cardiovascular disease. A vitamin B5 deficiency has been associated with hypertension, likely because of its requirement for adrenal function. 9–12
Quantity
60 Softgels
Dose
Recommended Adult Dose: 1 softgel 2 times per day with food or as directed by a health care practitioner. For use beyond 4 months, consult a health care practitioner.
• Promotes cardiovascular health, including support for dyslipidemia and elevated LDL-C • Provides the stable and bioavailable form of vitamin B5, necessary for the biosynthesis of coenzyme A • Coenzyme A is needed for multiple cellular effects, including energy production and fatty acid synthesis • Combined in an antioxidant formula, complexed with organic vegetables, berries, and anti-inflammatory botanicals 450 mg per serving allows for dosing used in clinical trials
Indications
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Cake\Http\Server->run() /home/ndassist/nhpassist.com/webroot/index.php, line 40
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• Promotes cardiovascular health, including support for dyslipidemia and elevated LDL-C • Provides the stable and bioavailable form of vitamin B5, necessary for the biosynthesis of coenzyme A • Coenzyme A is needed for multiple cellular effects, including energy production and fatty acid synthesis • Combined in an antioxidant formula, complexed with organic vegetables, berries, and anti-inflammatory botanicals 450 mg per serving allows for dosing used in clinical trials
Ingredients
Each Softgel Contains: D-Pantethine : 450 mg
Softgel (gelatin, glycerin, purified water).
Quantity
Warning (2)
: Trying to access array offset on value of type null [in /home/ndassist/nhpassist.com/templates/Products/index.php, line 2807]
/home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/View/View.php /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/View/View.php, line 1222
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Cake\Controller\ControllerFactory->handle() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Controller/ControllerFactory.php, line 115
Cake\Controller\ControllerFactory->invoke() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/BaseApplication.php, line 325
Cake\Http\BaseApplication->handle() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/Runner.php, line 86
Cake\Http\Runner->handle() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/Runner.php, line 86
Cake\Http\Runner->handle() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/Middleware/CsrfProtectionMiddleware.php, line 176
Cake\Http\Middleware\CsrfProtectionMiddleware->process() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/Runner.php, line 82
Cake\Http\Runner->handle() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/Runner.php, line 67
Cake\Http\Runner->run() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Routing/Middleware/RoutingMiddleware.php, line 198
Cake\Routing\Middleware\RoutingMiddleware->process() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/Runner.php, line 82
Cake\Http\Runner->handle() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Routing/Middleware/AssetMiddleware.php, line 68
Cake\Routing\Middleware\AssetMiddleware->process() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/Runner.php, line 82
Cake\Http\Runner->handle() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/Middleware/EncryptedCookieMiddleware.php, line 93
Cake\Http\Middleware\EncryptedCookieMiddleware->process() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/Runner.php, line 82
Cake\Http\Runner->handle() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Error/Middleware/ErrorHandlerMiddleware.php, line 149
Cake\Error\Middleware\ErrorHandlerMiddleware->process() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/Runner.php, line 82
Cake\Http\Runner->handle() /home/ndassist/nhpassist.com/vendor/cakephp/cakephp/src/Http/Runner.php, line 67
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Cake\Http\Server->run() /home/ndassist/nhpassist.com/webroot/index.php, line 40
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Dose
Recommended Adult Dose: 1 softgel 2 times per day with food or as directed by a health care practitioner. For use beyond 4 months, consult a health care practitioner.
